Bile Duct Cancer: Tests After Diagnosis

Woman having CT scan.

What tests might I have after being diagnosed?

After a diagnosis of bile duct cancer, you will likely need more tests. These tests help your healthcare providers learn more about the cancer. They can help show if the cancer has grown beyond the bile ducts into nearby tissues or spread to other parts of the body. The test results help your healthcare providers decide the best ways to treat the cancer. If you have any questions about these or other tests, be sure to talk with your healthcare team.

The tests you may have can include:

  • Endoscopic ultrasound

  • CT scan

  • MRI scan

  • Positron emission tomography (PET) scan

Imaging tests

Endoscopic ultrasound

Ultrasound tests use sound waves to create images of the inside of your body. For an endoscopic ultrasound, the healthcare provider uses a thin, lighted tube called an endoscope. This tool has a small ultrasound device on the end that sends out the sound waves. The endoscope is put in through your mouth and moved down into your intestine near the bile ducts. This lets the healthcare provider get closer to the bile ducts to use ultrasound, which allows for more detailed images. Your healthcare provider can use this test to look for cancer spread to nearby tissues.

CT scan

A CT scan can help your healthcare provider see if bile duct cancer has spread to nearby lymph nodes or to other organs. A CT scan gives a better picture than an ultrasound. For the test, you lie still on a table as it slowly slides through the center of the ring-shaped CT scanner. The scanner sends beams of X-rays at your belly (abdomen). A computer uses the X-rays to create detailed 3-D pictures of your insides.

A CT scan doesn't hurt. You may be asked to hold your breath 1 or more times during the scan. In some cases, you may be asked to drink a contrast dye before the scan. This helps show more details on the images. You may be told to not eat anything after drinking the contrast dye and before having the scan. The contrast dye will slowly pass through your system and come out in your bowel movements.


An MRI uses magnets, radio waves, and a computer to make detailed images of the inside of your body. MRIs might be used to see if cancer has spread outside of your bile ducts. Like a CT scan, an MRI can show more detail than X-rays. A special type of MRI called magnetic resonance cholangiopancreatography (MRCP) gives clear and detailed images of the organs and tissues in the liver, gallbladder, bile ducts, and pancreas. Another test called MR angiography (MRA) is an MRI study of the blood vessels. It gives the best pictures of the blood vessels in an area. MRI may also be used instead of a CT scan for people who are allergic to contrast dye.

For this test, you lie still on a narrow table as it passes into a large, narrow tube. While inside the tube, radio waves are sent through your body into your abdomen. These are not X-rays. They don't hurt. A computer uses the data from the radio waves to create detailed pictures of the inside of your body. You may need more than 1 set of images. Each set may take 2 to 15 minutes. The whole scan may take an hour or more. There are loud, grating, and thumping noises during the scan. You may be given earplugs, headphones, or both to wear. If you are claustrophobic, you may be given a sedative before having this test. A 2-way intercom will let you talk to the people controlling the scanner at all times. 

Positron emission tomography (PET) scan

For this test, a small amount of radioactive glucose (sugar) is injected into your blood through a vein. You then rest for an hour or so while the sugar is absorbed into the more active cells in your body. A scanner then creates pictures of the inside of the body and shows where the glucose is absorbed. These spots are called “hot spots.” Cancer cells absorb more glucose than normal cells, so this scan can help show where cancer may have spread in the body. This test can also be used to show the difference between active cancer cells and scar tissue. A PET scan may be combined with a CT scan to get more detailed information. This is called a PET-CT scan.

Working with your healthcare provider

Your healthcare provider will talk with you about which tests you’ll need to have and what the tests will be like. Make sure to get ready for the tests as instructed. Ask questions and talk about any concerns you have.

Online Medical Reviewer: Kimberly Stump-Sutliff RN MSN AOCNS
Online Medical Reviewer: Louise Cunningham RN BSN
Online Medical Reviewer: Todd Gersten MD
Date Last Reviewed: 2/1/2021
© 2021 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare provider's instructions.